Biocore® VDR BsmI PCR kit
Biocore® VDR BsmI — a modern PCR test system for genotyping the BsmI polymorphism of the human VDR gene using real-time polymerase chain reaction (PCR-RT) from the Ukrainian developer Biocore Technology.
The VDR gene encodes the vitamin D receptor — a protein that binds to the active form of vitamin D and regulates the activity of hundreds of other genes responsible for calcium and phosphorus metabolism, bone mineralisation and the functioning of the immune system.
The BsmI polymorphism (p.1024+283G>A) is located in the non-coding region of the VDR gene. It does not result in a change in the amino acid sequence of the protein, but may influence gene expression by altering mRNA stability or the splicing process. Consequently, the body’s sensitivity to vitamin D may vary among carriers of different polymorphism variants.
Registered name: ‘Biocore® VDR BsmI’ diagnostic kit for screening the Bsm1 polymorphism in the human VDR (vitamin D receptor) gene using real-time PCR
Catalogue number: CM-VDR/B 502-100
Price on request
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