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Biocore® Lactase Deficiency PCR Kit
Biocore® Lactase Deficiency — a state-of-the-art PCR test system for genotyping the -13910T>C polymorphism of the human MCM6 gene using real-time polymerase chain reaction (PCR-RT) from the Ukrainian developer Biocore Technology.
Registered name: ‘Biocore® Lactase Deficiency’ diagnostic kit for genotyping the -13910T>C polymorphism of the human MCM6 gene by real-time PCR
Catalogue number: CM-LI 503-100
Lactase deficiency is a condition in which the body is unable to fully break down lactose (milk sugar) due to a deficiency or reduced activity of the lactase enzyme in the small intestine. Clinically, this manifests as abdominal distension, flatulence, diarrhoea and pain following the consumption of dairy products.
One of the most common causes is primary lactase deficiency — a hereditary metabolic condition in which lactase activity gradually decreases after infancy. The level of enzyme activity is largely determined by the -13910 C>T (rs4988235) polymorphism of the MCM6 gene, which regulates the expression of the lactase gene (LCT). Detection of this polymorphism enables us to identify a genetic predisposition to lactase deficiency and to provide personalised dietary recommendations for the patient.
Price on request
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